Pharmacotherapy teaching equips healthcare learners to master medication use for disease treatment and prevention. It moves beyond memorizing drug facts to fostering critical thinking and clinical reasoning. The core involves a systematic process: identifying drug therapy problems, setting therapeutic goals, selecting optimal regimens based on patient-specific factors (e.g., age, kidney function), and establishing monitoring plans for efficacy and toxicity. Instruction blends foundational pharmacology (how drugs work) with patient-centered care, emphasizing communication, adherence, and safety vigilance. Modern methodologies are key, utilizing case-based learning for application, interprofessional education to mimic real-world teams, and clinical rotations for hands-on experience. The ultimate goal is to produce prescribers who are not only competent and evidence-based but also mindful of safety, cost, and the individual patient to ensure optimal outcomes.